Skull and Crossbones

Primarily represents death, poison, or extreme danger. It is the iconic symbol for hazardous substances and is also associated with pirates (the Jolly Roger flag).

While it can be used for figurative death (like laughter), the 💀 (Skull) emoji is more common for that purpose. This emoji retains a stronger connection to literal danger.

Given its long history in Unicode, it has universal support across all platforms.